Heavy drinking early in life raises prostate cancer risk

[MillCreek]

http://www.urologytimes.com/prostate-cancer/does-early-life-alcohol-intake-raise-high-grade-pca-risk?elq_cid=673878&elq_mid=3331&rememberme=1

http://cancerpreventionresearch.aacrjournals.org/content/early/2018/08/16/1940-6207.CAPR-18-0057.long

Seven or more drinks per week from ages 15 to 50 equals a 3.2 times greater risk to be diagnosed with high-grade prostate cancer compared to non-drinkers.

This may influence your thoughts on getting a periodic PSA and/or DRE as part of a yearly medical workup.

[K Frame]

High-grade prostate cancer?

Is there a super deluxe prostate cancer that comes with rich Corinthian leather?

[lee n. field]

Yeah, what does "high grade" mean in this context?   

[brimic]

Yeah, what does "high grade" mean in this context?   

Its only for people who drink high grade alcohol...

[MillCreek]

High grade prostate cancer is generally more aggressive, grows faster and spreads wider and has a poorer prognosis.  These have scores on 8-10 on the Gleason scale, which is a measurement of a prostate biopsy and other factors that help guide treatment.

[MechAg94]

Seven or more drinks per week.  All at once or spaced out?  Does that count little old ladies who drink a glass of wine every day? 

[BobR]

Yeah, what does "high grade" mean in this context?   

Means you will die after it metastasizes to your bones and liver, and it will do it a lot quicker than a "low grade" cancer.

bob

[freakazoid]

These sections confuse me.

They found that men who drank seven or more drinks weekly at ages 15 to 19 years were 3.2 times more likely to be diagnosed with high-grade prostate cancer later in life compared to non-drinkers. The authors noted similar associations between heavier drinking and prostate cancer severity for ages 20 to 29, 30 to 39, and 40 to 49 years. Men with a cumulative lifetime intake of seven or more alcoholic beverages weekly also were 3.2 times more likely than lifetime nondrinkers to have high-grade prostate cancer later in life.

So if you only drank that much between 15-19, but afterwards stopped drinking that much, you are 3.2 times more likely? And the same effect with the other age groups? And also, if you didn't stop it was still 3.2?

There was no association, however, between alcohol intake at ages 15 to 19 years and overall prostate cancer diagnosis at biopsy.

And here it's saying that there actually ISN'T any risk for it if you drink that much 15-19?

 

[lee n. field]

High grade prostate cancer is generally more aggressive, grows faster and spreads wider and has a poorer prognosis.  These have scores on 8-10 on the Gleason scale, which is a measurement of a prostate biopsy and other factors that help guide treatment.

Beyond the fact that it wasn't the lowest,  I don't remember now what my Gleason score was, or even if they ever told me. 

[Scout26]

What does it say about later in life ??  [/Malcom Reynolds voice]

[freakazoid]

What does it say about later in life ??  [/Malcom Reynolds voice]

No risk. Drink away.